Mahmoud Abdel Aziz was born in Alexandria, Egypt to a middle class family. He studied Agricultural Sciences and during his college days he practiced acting through the university theatre.

He started his acting career by taking a role in "Al Dawama" TV show in the mid 70s with Nelly and Mahmoud Yassin after which he entered the cinema world for the first time through "Al Hafeed" an all time Egyptian film classic. Mahmoud Abdel Aziz starred in over 25 movies during the late 70s and early 80s while his popularity was increasing dramatically, most of his movies at the time were categorized as romantic drama.

His acting path has matured when he started taking different roles which really exposed his talent. He was known to be equally adept at comedy and drama.

The 1980s marked Mahmoud Abdel Aziz as a superstar when he starred in very successful movies like "El Aar", "El Keef" and "Rafat El Haggan" TV Series which is one of the most popular works of Egyptian television based on the true story of the renowned Egyptian spy who was planted in Israel for over 20 years before the 6 days war.

Mahmoud Abdel Aziz has starred in over 100 movies and he can still surprise his audience with great work such as Bab El Khalk (2012) TV Series after 7 years of absence from the Egyptian TV.

He has two children Mohamed Mahmoud Abdel Aziz a film producer and director; and Karim Mahmoud Abdel Aziz.